Bovine breast growth hormones

This report was updated on April 23, to clarify quantities of growth hormone found in milk and those used in the rat study. On November 5, , following extensive review of the data to support the safety and effectiveness of the product, the Food and Drug Administration FDA or Agency approved the Monsanto Companys New Animal Drug Application for Posilac containing a recombinant bovine growth hormone rbGH also known as recombinant bovine somatotropin, rbST, or Sometribove. Growth hormone GH is a protein hormone produced in the pituitary gland of animals including humans and is essential for normal growth, development, and health maintenance. Approximately 60 years ago, it was discovered that injecting cows with GH extracted from cattle pituitary glands increased milk production. In the s, it became technically possible and economically feasible to produce large quantities of bovine GH bGH using recombinant DNA processes. In order to grant approval of Posilac, FDA determined, among other things, that food products from cows treated with rbGH are safe for consumption by humans.

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Milk occupies a special place in our lives and language. Fourteen years ago, after a lengthy review, the FDA approved a protein called recombinant bovine somatotropin rbST , or bovine growth hormone, that stimulates milk production in dairy cows. Thus, low levels of bST are found in milk from all cows, both supplemented and unsupplemented. Comprehensive and sophisticated studies by academics and government regulatory agencies around the world have found no difference in the composition of the milk or meat from bST-supplemented cows. From the beginning, farmers loved rbST, which is now used in approximately one-third of U.
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Breast Cancer Group to Eli Lilly: Stop Selling Bovine Growth Hormone

Comment in Science. Scientists in the Food and Drug Administration FDA , after reviewing the scientific literature and evaluating studies conducted by pharmaceutical companies, have concluded that the use of recombinant bovine growth hormone rbGH in dairy cattle presents no increased health risk to consumers. Bovine GH is not biologically active in humans, and oral toxicity studies have demonstrated that rbGH is not orally active in rats, a species responsive to parenterally administered bGH. However, oral toxicity studies have shown that bovine IGF-I lacks oral activity in rats.
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Monsanto has suffered a number of technological and public relations"glitches" over the past few years, including the massive marketplace failureof its billion-dollar flagship product, rBGH. Wall Street analysts told Business Week magazine in that dueto farmer and consumer opposition and the fact that rBGH damages thehealth of cows the drug was a total failure, and that in economic terms itshould be taken off the market. In scientific and public health terms, data continues to pile up thatsignificantly increased levels of the human growth hormone factor IGF-1in genetically engineered milk and dairy products constitute a serioushuman health risk for increased breast and colon cancer.
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